The pair are said to have clashed in a New York nightclub and the R&B star was treated in hospital after he was allegedly bottled by one of the rival hitmaker's entourage.
The singer posted a gruesome snap of his injury on his Twitter page, but later removed it.
The two musicians have had a long-running feud over Drake's dalliance with Chris's ex Rihanna.
But when they met at WIP club last night, Chris is thought to have sent a bottle of champagne to Drake's table as a peace offering.
Unconfirmed reports say the bottle was returned with a note referring to Rihanna which read: "I'm f****** the love of your life, deal with it."
Chris then flew into a rage and confronted Drake, who threw a punch.
Before the Turn Up The Music singer could retaliate, onlookers say another man hit him in the face with a bottle.
Security broke up the fracas and Drake left with his entourage, according to website MediaTakeOut.com.
Chris, who showed the bleeding chin to his ten million followers before changing his mind, then took himself to hospital.
But Buzzlov3.com says:
Apparently there was an altercation that resulted in a member of Drake's camp throwing aThe details are super hazy at this point, with some even saying rapper Meek Mill was also involved in the altercation last night. at Breezy. In true Chris fashion, he took to twitter to vent his frustrations. He also tweeted a picture of his injury.
Hold up Hold up whats a story with out a Mediatakeout? lol
According to MULTIPLE MediaTakeOut.com snitches inside, Chris and Drake have had a DIFFICULT relationship since three years ago - when Rihanna CHEATED on Chris, with Drake. Chris has HELD A GRUDGE against Drake for years.
Well last night at WIP, we're told that Chris reportedly sent over a bottle of champagne to Drake's table, as a sort of peace offering. We're not sure WHAT happened next, but we're hearing UNCONFIRMED REPORTS that Drake sent the bottle back to Chris with a message to the effect of - "I'm f*ckng the love of your life [Rihanna], deal with it."
Whatever message Drake sent back caused Chris to immediately fly into a rage - and he CONFRONTED Drake and his entourage - which included ANOTHER Chris Brown rival, rapper Meek Mill. Meek Mill also had a relationship with Rihanna.
Well according to our snitch, Drake PUNCHED Chris in the face and before Chris could retaliate, someone (#teamnosnitch#) popped Chris in the mouth with a BOTTLE, multiple times. And as a result, Chris was LEAKING LIKE A FAUCET!!!
Security immediately swooped in and broke up the fight. Drake and 'em immediately LEFT the club, before POLICE arrived. Chris, we're told left under his own power - and later went to the HOSPITAL, to get his face sewn shut.
*cues* LORD KNOWS
"who should I be afraid of?
Bought a white Ghost, now shit is gettin' spooky
Very, very scary, like shit you see in the movies"